RESOLUTION OF RECURRENT MALIGNANT GANGLIOGLIOMA AFTER TREATMENT WITH CIS-RETINOIC ACID

Authors
KABA SE LANGFORD LA YUNG WKA KYRITSIS AP
Citation
Se. Kaba et al., RESOLUTION OF RECURRENT MALIGNANT GANGLIOGLIOMA AFTER TREATMENT WITH CIS-RETINOIC ACID, Journal of neuro-oncology, 30(1), 1996, pp. 55-60
Citations number
20
Categorie Soggetti
Clinical Neurology",Oncology
Journal title
Journal of neuro-oncology → ACNP
ISSN journal
0167594X
Volume
30
Issue
1
Year of publication
1996
Pages
55 - 60
Database
ISI
SICI code
0167-594X(1996)30:1<55:RORMGA>2.0.ZU;2-0
Abstract
Ganglioglioma is an uncommon brain tumor with glial and neuronal cellu lar components and a somewhat benign course. We are presenting an unus ual case of ganglioglioma with malignant transformation in both cellul ar components associated with an aggressive clinical course. An almost complete resolution of the recurrent progressing tumor was achieved a fter treatment with cis-retinoic acid (cRA) as a single agent. A possi ble differential effect of cRA on the neuronal component of the tumor is suggested.