Tooth eruption is an essential process for the survival of many differ
ent species and although the movement of teeth into function has been
the subject of extensive research there is no consensus as to the mech
anisms involved. Recent understanding of the mechanisms of cell activa
tion and regulation has widened the scope for further research at the
molecular level. This paper reviews the evidence for an eruptive force
, its direction and source. The relationships between the eruptive for
ce and molecular mechanisms of cell activation remain to be determined
.