CAVERNOUS SINUS SYNDROME IN HODGKINS-DISEASE

Hodgkin's disease has not been reported to produce an isolated caverno us sinus syndrome, although this phenomenon is well-described in non-H odgkin's lym phoma. We review the 16 cases of cavernous sinus syndrome caused by non-Hodgkin's lymphoma and report two patients with Hodgkin 's disease in clinical remission who developed recurrent disease in th e cavernous sinus. MRI revealed a mass lesion in the left cavernous si nus in each patient. Corticosteroids and radiation therapy were effect ive palliative measures. In both patients, recurrence in the cavernous sinus preceded other systemic evidence of recurrent Hodgkin's disease .