STUDIES ON THE CONSTITUENTS OF CYCLANTHERA-PEDATA (CAIGUA) SEEDS - ISOLATION AND CHARACTERIZATION OF 6 NEW CUCURBITACIN GLYCOSIDES

Six new cucurbitacin glycosides were isolated from the seeds of Cyclan thera pedata Schrab (Cucurbitaceae). Their structures were elucidated on the basis of spectral and chemical data to be eta-glucopyranosyl-be ta-D-glucopyranosyl)oxy]-3,16 entahydroxy-29-norcucurbita-1,3,5(10)-tr ien-11-one (1), a-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-3,16 etr ahydroxy-29-norcucurbita-1,3,5(10)-trien-11-one (2), 25-acetoxy-2-(bet a-D-glucopyranosyloxy)-3,16 etrahydroxy-29-norcucurbita-1,3,5(10)-trie n-11-one (3), a-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-3,16 alpha ,20-trihydroxy-29-norcucurbita-1,3,5-(10) triene-11,22-dione (4), 3 et a-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-16 alpha,20,22,25-tetrah ydroxycucurbit-5-en-11-one (5), 3-beta-(beta-D-glucopyranosyloxy)-25-a cetoxy-16 alpha,20,22,-trihdroxy-cucurbit 5-en-11-one (6).