A retrospective study is presented of 26 uncemented bipolar hip replac
ements for avascular necrosis of the femoral head due to sickle cell d
isease which were carried out between 1987 and 1992. All patients were
treated according to a protocol. The average follow up was 4.6 years
(range 2.1 to 7 years). After operation, the average Harris hip score
improved from 36 to 88. Bone culture was positive for bacterial growth
in 4 hips (coagulase negative staphylococcus in 3). There was progres
sive wear of acetabular articular cartilage in 2 cases, but no clinica
l or radiological evidence of loosening of the femoral stem. Seventeen
complications occurred in 9 of the 21 patients (5 in one patient). A
longitudinal split of the femur was the commonest operative complicati
on and occurred in 5 hips. Femoral medullary sclerosis was seen in 8 c
ases. Patients with sickle cell disease have a high risk of complicati
ons, but this type of hip replacement should be considered in carefull
y selected patients who have avascular necrosis of the femoral head.