Aa. Campbell et al., SURFACE-INDUCED MINERALIZATION - A NEW METHOD FOR PRODUCING CALCIUM-PHOSPHATE COATINGS, Journal of biomedical materials research, 32(1), 1996, pp. 111-118
Calcium phosphate coatings were nucleated and grown from aqueous solut
ion onto titanium metal substrates via surface-induced mineralization
(SIM) processing techniques. This process is based on the observation
that in nature organisms use biopolymers to produce ceramic composites
, such as teeth, bones, and shells. The SIM process involves modificat
ion of a surface to introduce surface functionalization followed by im
mersion in aqueous supersaturated calcium phosphate solutions. This lo
w-temperature process (< 100 degrees C) has advantages over convention
al methods of calcium phosphate deposition in that uniform coatings ar
e produced onto complex-shaped and/or microporous samples. Additionall
y, because it is a low-temperature process, control of the phase and c
rystallinity of the deposited material can be maintained. (C) 1996 Joh
n Wiley & Sons, Inc.