THERAPEUTIC THROMBOLYSIS USING RECOMBINAN T TISSUE-TYPE PLASMINOGEN-ACTIVATOR (RT-PA) FOR A RECURRENT THROMBOSIS OF A TRICUSPID-VALVE PROSTHESIS DURING PREGNANCY

The authors report a case of a woman who had two episodes of a tricusp id Saint-Jude prosthesis thrombosis treated with fibrinolysis using rt -PA, during the fourth month of pregnancy. A first course of thromboly tic therapy was successful with normal valve function despite threaten ing abortion and uterine bleeding. An early rethrombosis ct the prosth etic valve and a failure of a second course of thrombolysis required t he interruption of pregnancy with a replacement of the tricuspid valve prosthesis.