PURPOSE: To evaluate the data acquired over 2 1/2 years regarding the
use of mechanical thrombolysis as the routine, preferred treatment for
thrombosed access grafts in a large patient population undergoing hem
odialysis. MATERIALS AND METHODS: Mechanical thrombolysis was performe
d in 1,176 cases. Data were collected on the success rate, complicatio
n rate, long-term patency, and presence and location of stenosis. The
results of mechanical thrombolysis were compared with those of surgery
. All data were collected prospectively. RESULTS: Thrombosed grafts we
re treated successfully in 1,123 of 1,176 cases (95%). Minor complicat
ions occurred in 34 cases (3%). Venous stenosis was present in 1,054 c
ases (90%). Long-term patency rates were 74% at 30 days, 52% at 90 day
s, and 17% at 360 days. The thrombosis rate per patient per year and t
he number of patients who required graft revision or replacement decre
ased in comparison with the results obtained with surgical treatment.
CONCLUSION: Mechanical thrombolysis was effective, quick, and safe. Pe
rcutaneous treatment should be adopted as the treatment of choice for
thrombosed hemodialysis access grafts.