T. Fekner et al., SYNTHESES OF (6S,7S)-DEACETOXYCEPHALOSPORANIC AND (6S,7R)-DEACETOXYCEPHALOSPORANIC ACIDS FROM 6-AMINOPENICILLANIC ACID, Chemical communications, (16), 1996, pp. 1989-1990
Two practical (i.e. applicable to multigram scale synthesis) approache
s to (6S,7S)-cephalosporins (i.e. the enantiomers of naturally occurin
g cephalosporins) and the (6S)-epimers of cephalosporins from readily
available (2S,5R,6R)-6-aminopenicillanic acid 1 are described.