D. Lurton et al., WIDESPREAD ECTOPIC NEUROPEPTIDE-Y IMMUNOREACTIVITY IN CONTRALATERAL MOSSY FIBERS AFTER A UNILATERAL INTRAHIPPOCAMPAL KAINIC ACID INJECTION IN THE RAT, Neuroscience letters, 213(3), 1996, pp. 181-184
Granule cells of the dentate gyms can express neuropeptide-Y (NPY) in
several models of epilepsy involving limbic seizures, however, the nat
ure of this ectopic expression is not well understood at present. We h
ave studied the expression of NPY-immunoreactivity in messy fibres con
tralateral to a unilateral intrahippocampal injection of kainic acid a
nd report that ectopic messy fibre NPY-immunoreactivity is observed th
roughout the contralateral hippocampus.