Lower rates of transplantation among minority groups are a nationally
recognized phenomenon. Native Americans (NA) nationally have nearly fo
ur times the risk of end-stage renal disease (ESRD) as compared with w
hite (W) Americans and are significantly overrepresented in the Networ
k 15 ESRD population. To understand more about NA and W transplant rat
es, we looked at all reported Arizona (AZ) and New Mexico (NM) residen
t cases from the Network No. 15 data base. Age of onset, sex, primary
diagnosis, payment source, transplant donor source, and other factors
were examined. NA experienced a slightly earlier onset of ESRD than W,
and diabetes mellitus was the primary ESRD diagnosis for 63-73% of NA
and for 34-39% of W. Because age distribution and frequency of diabet
es mellitus of the NA ESRD population differ from those of W in the Ne
twork, age-specific and diagnosis-specific transplant rates were exami
ned. Age-adjusted transplant rates per 100 ESRD patients for AZ were 1
6.4 (NA) and 21.0 (W) and for NM 14.2 (NA) and 22.4 (W). Diagnosis-spe
cific age-adjusted transplant rates for patients with the primary diag
noses of diabetes mellitus and glomerulonephritis, the two most common
causes of ESRD among NA, showed a large difference between W and NA r
ates. Age-adjusted rates for diabetics were: AZ 8.5% (NA) and 14.5% (W
); NM 9.8% (NA) and 15.9% (W). Age-adjusted rates for patients with gl
omerulonephritis were: AZ 23.7% (NA) and 28.0% (W); NM 22.3% (NA) and
33.0% (W). In all comparisons and in both the W and NA ESRD population
s, women were transplanted at lower rates than men. NA experienced a g
reater delay from onset of treated ESRD to transplant than W. Payment
source and transplant donor source did not appear to be significantly
different between NA and W. The lower transplant rates in NA versus W
in Network No. 15 cannot be explained by age or diagnosis-specific fac
tors.