NOVEL TRANSCRIBED SEQUENCES REPRESENTED IN THE COMPLEX GENOMIC REGION5Q13

Authors
MORRISON KE QURESHI SJ ANDERSON S BORRETT JP THEODOSIOU A RODRIGUES N BLAKE D NESBIT A DAVIES KE PORTEOUS DJ BROOKES AJ
Citation
Ke. Morrison et al., NOVEL TRANSCRIBED SEQUENCES REPRESENTED IN THE COMPLEX GENOMIC REGION5Q13, Biochimica et biophysica acta, N. Gene structure and expression, 1308(2), 1996, pp. 97-102
Citations number
37
Categorie Soggetti
Biology,Biophysics,"Biothechnology & Applied Migrobiology
Journal title
Biochimica et biophysica acta, N. Gene structure and expression → ACNP
ISSN journal
01674781
Volume
1308
Issue
2
Year of publication
1996
Pages
97 - 102
Database
ISI
SICI code
0167-4781(1996)1308:2<97:NTSRIT>2.0.ZU;2-2
Abstract
YACs from the complex repetitive human genomic region 5q13, spanning t he spinal muscular atrophy (SMA) locus, have been searched for transcr ibed sequences using the method of End Ligation Coincident Sequence Cl oning. Six transcripts (PT1-6) have been identified, three of which (P T4, PT5 and PT6) are novel. Five of these elements hybridise to multip le loci in 5q13, but PT5 is single copy and maps very close to markers that show linkage disequilibrium with SMA.