Background: Respiratory insufficiency associated with morbid obesity c
an include sleep apnea syndrome (SAS), obesity hypoventilation syndrom
e (OHS), or a combination of both. The aim of our study was to determi
ne the safety and effectiveness of vertical banded gastroplasty (VBG)
in the treatment of severely obese patients with respiratory insuffici
ency. Methods: From 1983 to 1994, 35 patients (25 males, ten females)
who met the criteria for either SAS and OHS (19 patients) or SAS alone
(16 patients) underwent VBG. Results: Six patients (17%) died of subs
equent pulmonary-cardiac disease despite significant weight loss. Need
for nasal continuous positive airway pressure (CPAP) decreased after
VBG from 68% of patients preoperatively to 22% postoperatively. Of the
ten patients with sleep studies, the apnea/hyponea index decreased fr
om 45 +/- 11 events per h preoperatively to 12 +/- 6 events per h post
operatively, while per cent ideal body weight (%IBW) also decreased (p
re-VBG: 268 +/- 12, post-VBG: 204 +/- 12). Of the seven patients with
arterial blood gases, PaCO2 decreased from 55 +/- 4 torr preoperativel
y to 41 +/- 3 torr postoperatively, and PaO2 increased from 50 +/- 4 t
orr preoperatively to 73 +/- 6 torr postoperatively, while %IBW decrea
sed (pre-VBG: 263 +/- 16, post-VBG: 193 +/- 14). Conclusion: Respirato
ry insufficiency is a life-threatening complication of morbid obesity.
In morbidly obese patients with respiratory insufficiency, VBG offers
improvement in both SAS and OHS. Respiratory insufficiency due to obe
sity should be considered a strong indication for VBG.