NEONATAL DIABETES-MELLITUS WITH AUTOIMMUN E-DISEASE

Background. - Insulin-dependent diabetes mellitus can be associated to an auto-immune disease. A similar association may be seen in the neon ate. Case report. - A one-day-old boy was admitted for ketoacidosis du e to diabetes mellitus. Investigation showed that he also suffered fro m an auto-immune enteropathy with several types of autoantibodies, par ticularly anti-enterocytes antibodies. Immunotherapy was ineffective. Multi-organ lesions developed subsequently, particularly a pulmonary d isease responsible for the death at the age of 2 years. Conclusion. - Physiopathology of this association remains unclear and the report of further cases should help improve our knowledge.