MULTITRACER STUDY ON DISTRIBUTION OF CARRIER-FREE RADIOACTIVE ISOTOPES IN ORGANS OF RATS

Citation
Sh. Enomoto et al., MULTITRACER STUDY ON DISTRIBUTION OF CARRIER-FREE RADIOACTIVE ISOTOPES IN ORGANS OF RATS, Journal of radioanalytical and nuclear chemistry, 205(2), 1996, pp. 277-282
Citations number
13
Categorie Soggetti
Chemistry Analytical","Nuclear Sciences & Tecnology","Chemistry Inorganic & Nuclear
ISSN journal
02365731
Volume
205
Issue
2
Year of publication
1996
Pages
277 - 282
Database
ISI
SICI code
0236-5731(1996)205:2<277:MSODOC>2.0.ZU;2-1
Abstract
Multitracer, a new tracer technique developed by us, can analyze metab olism and behavior of different elements in the living bodies simultan eously. We were able to reproduce completely the results on the behavi or of various elements obtained by individual experiments of our precu rsors only by a single run of this technique. At the same time, we cou ld also show the behavior and interaction of many other trace elements which past researchers did not pay attention to. For example, our res ults on the behavior of rare-earth elements suggested that there is a correlation between their uptakes and ion radii. We also discovered th at affinities of platinum and iridium for their binding proteins were changed the latter being increased, in the case of zinc deficiency. In this article, we discuss the usefulness of the multitracer technique in the studies of trace elements in living bodies.