Sh. Enomoto et al., MULTITRACER STUDY ON DISTRIBUTION OF CARRIER-FREE RADIOACTIVE ISOTOPES IN ORGANS OF RATS, Journal of radioanalytical and nuclear chemistry, 205(2), 1996, pp. 277-282
Multitracer, a new tracer technique developed by us, can analyze metab
olism and behavior of different elements in the living bodies simultan
eously. We were able to reproduce completely the results on the behavi
or of various elements obtained by individual experiments of our precu
rsors only by a single run of this technique. At the same time, we cou
ld also show the behavior and interaction of many other trace elements
which past researchers did not pay attention to. For example, our res
ults on the behavior of rare-earth elements suggested that there is a
correlation between their uptakes and ion radii. We also discovered th
at affinities of platinum and iridium for their binding proteins were
changed the latter being increased, in the case of zinc deficiency. In
this article, we discuss the usefulness of the multitracer technique
in the studies of trace elements in living bodies.