ASYMMETRIC FRIEDEL-CRAFTS REACTION - AN APPLICATION TO THE SYNTHESIS OF AN ETODOLAC ANALOG

Authors
CABRAL LM COSTA PRR VASCONCELLOS MLAA BARREIRO EJ CASTRO RN
Citation
Lm. Cabral et al., ASYMMETRIC FRIEDEL-CRAFTS REACTION - AN APPLICATION TO THE SYNTHESIS OF AN ETODOLAC ANALOG, Synthetic communications, 26(19), 1996, pp. 3671-3676
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
26
Issue
19
Year of publication
1996
Pages
3671 - 3676
Database
ISI
SICI code
0039-7911(1996)26:19<3671:AFR-AA>2.0.ZU;2-7
Abstract
An Etodolac analogue, (-)-7, was prepared in 40% ee. by asymmetric Fri edel-Crafts reaction, involving tryptophol 4 and chiral beta-ketobutyr ate 5f, followed by hydrolysis.