Zg. Zhang et al., STUDY OF INTERACTIONS BETWEEN TITANOCENE DICHLORIDE AND MONONUCLEOTIDES BY HIGH-RESOLUTION H-1-NUCLEAR AND P-31-NUCLEAR MAGNETIC-RESONANCE, Transition metal chemistry, 21(4), 1996, pp. 322-326
The interactions between Cp(2)TiCl(2) and mononucleotides such as 5'-A
MP, 5'-CMP, 5'-GMP and 5'-TMP were investigated by high-resolution H-1
- and P-31-n.m.r. The results suggest that phosphate (O) and nucleobas
e (N) are all important targets of Cp(2)TiCl(2). The mechanism of the
Cp(2)TiCl(2)-DNA interaction is discussed.