Lc. Collins et al., SMOKING MULTIPLE HIGH-NICOTINE VERSUS LOW-NICOTINE CIGARETTES - IMPACT ON RESTING ENERGY-EXPENDITURE, Metabolism, clinical and experimental, 45(8), 1996, pp. 923-926
The thermic effect of smoking multiple cigarettes varying substantiall
y in nicotine yield was investigated. Three treatments were imposed: n
onsmoking at baseline, smoking six low-nicotine (0.8 mg nicotine) ciga
rettes (LOW), and smoking six high-nicotine (1.74 mg nicotine) cigaret
tes (HIGH). An initial increase of 6.8% in resting energy expenditure
(REE) above baseline REE occurred after consumption of two consecutive
cigarettes for both the HIGH and LOW treatments. With consumption of
more cigarettes, the peak increase for the HIGH treatment was 9.3%, si
gnificantly greater than the peak of 5.9% for the LOW. Averaged over 2
hours, the HIGH treatment significantly increased REE by 6.9% and the
LOW treatment significantly increased REE by 5.2%. Expired carbon mon
oxide (GO) measurements indicated that LOW cigarettes were smoked more
aggressively than HIGH cigarettes. It was concluded that, initially,
the nicotine yield of cigarettes is not an important influence on the
thermic effect of smoking. But over a longer period and after multiple
cigarettes, the nicotine yield may become an important influential fa
ctor. Copyright (C) 1996 by W.B. Saunders Company