SMOKING MULTIPLE HIGH-NICOTINE VERSUS LOW-NICOTINE CIGARETTES - IMPACT ON RESTING ENERGY-EXPENDITURE

The thermic effect of smoking multiple cigarettes varying substantiall y in nicotine yield was investigated. Three treatments were imposed: n onsmoking at baseline, smoking six low-nicotine (0.8 mg nicotine) ciga rettes (LOW), and smoking six high-nicotine (1.74 mg nicotine) cigaret tes (HIGH). An initial increase of 6.8% in resting energy expenditure (REE) above baseline REE occurred after consumption of two consecutive cigarettes for both the HIGH and LOW treatments. With consumption of more cigarettes, the peak increase for the HIGH treatment was 9.3%, si gnificantly greater than the peak of 5.9% for the LOW. Averaged over 2 hours, the HIGH treatment significantly increased REE by 6.9% and the LOW treatment significantly increased REE by 5.2%. Expired carbon mon oxide (GO) measurements indicated that LOW cigarettes were smoked more aggressively than HIGH cigarettes. It was concluded that, initially, the nicotine yield of cigarettes is not an important influence on the thermic effect of smoking. But over a longer period and after multiple cigarettes, the nicotine yield may become an important influential fa ctor. Copyright (C) 1996 by W.B. Saunders Company