HEMORHEOLOGICAL OBSERVATION ON 139 CASES OF ESSENTIAL-HYPERTENSION BYCASSON EQUATION

Attention has been paid to the relationship between hypertension and h emorheology by several authors and their results showed that hypertens ion was associated with altered blood viscosity. The previous reports were empirically from one or several points of blood viscosity under d ifferent shear rates. Can we consider the pathogenesis from the whole curve of blood viscosity versus shear rate? Our aims are to use new co ncepts to reveal hemorheological properties and to analyze the patholo gical changes for essential hypertension by a Casson equation which su mmarize the whole curve of blood viscosity versus various shear rate. We use two parameters which are derived from Casson equation and regre ssed from all the data of shear stress and shear rate, i.e. Casson yie ld stress and Casson viscosity, to describe the hemorheological change s for 139 cases of hypertension patients. Our results showed that: 1) The total patients show increase of the two Casson parameters, especia lly for female patients; 2) Essential hypertension in the early stage may be not closely connected to Casson parameters; 3) When essential h ypertension begins to complicate with cerebral and coronary heart dise ases, or some other diseases, the patients show remarked changes in th e two Casson parameters, especially for Casson yield stress; 4) Yield stress may be the best parameter to show abnormality in hemorheology, and Casson viscosity is also good to show the abnormality in hemorheol ogy; 5) Yield stress and Casson viscosity are proportionally correlate d to hematocrit and plasma viscosity, especially for the yield stress.