The object of the neurosurgeons daily endeavour, the human brain, is l
ess well understood in its overall organization than any other organ.
This puts the neurosurgeon in a very difficult position. However, a su
bstantial body of knowledge has been accumulated during recent years,
and scientists from a variety of different disciplines have worked out
theoretical frameworks to accomodate the available data. Here we pres
ent some of the evolving concepts on the organization of the substrate
of the mind. Review of the literature shows that application of mathe
matical neural network models to the nervous system is very successful
in explaining function. An implicit aspect of neural network models i
s that information storage is not localized in certain neurons but tha
t the information stored as the global pattern of activity in the netw
ork. Because networks of the brain involve often millions of neurons,
exact identification and comparison with the theoretical models is not
possible today.