Wt. Lawrence, TREATMENT OF EARLOBE KELOIDS WITH SURGERY PLUS ADJUVANT INTRALESIONALVERAPAMIL AND PRESSURE EARRINGS, Annals of plastic surgery, 37(2), 1996, pp. 167-169
Treatment for keloids remains less than ideal. Previous discouraging r
esults prompted a change in the author's standard treatment for keloid
s to surgery plus adjuvant intralesional verapamil and pressure earrin
gs. Intralesional verapamil (2.5 mg per milliliter) was administered 7
to 14 days after keloid removal and again approximately 1 month after
removal when possible, Between 0.5 ml and 2.0 ml was administered eac
h time, depending on the size of the keloid. Patients were instructed
to wear pressure earrings essentially continuously for a minimum of 6
months after excision. Thirty-five African American patients with 45 e
arlobe keloids were treated with this regimen. Information regarding r
ecurrence was obtained by follow-up, mail, or phone call from 31 patie
nts (89%) with 40 keloids (89%). Minimum follow-up for inclusion was 6
months and average follow-up was 28 months. Twenty-two keloids (55%)
in 16 patients (52%) were cured by this treatment modality. There were
no significant differences in recurrence rates related to sex, age, k
eloid size, length of time the keloid was present, how long the ears h
ad been pierced, and how many verapamil injections were received. Ther
e was a trend toward an increased recurrence rate for previously treat
ed keloids. Though not optimal, this regimen is superior to some previ
ously evaluated regimens.