Hl. Koh et al., VISUALIZATION BY MAGNETIC-RESONANCE-IMAGING OF FOCAL CARTILAGE LESIONS IN THE EXCISED MINIPIG KNEE, Journal of orthopaedic research, 14(4), 1996, pp. 554-561
This study showed that magnetic resonance imaging can be used to visua
lize partial thickness cartilage lesions, 0.7 x 10 mm in area and 0.5
mm in depth, surgically induced in the femur (femoropatellar compartme
nt) of a mini-pig knee joint. Formalin-fixed joints, intact as well as
disarticulated, were studied by high resolution imaging using a 2.35
T, 31 cm horizontal-bore superconducting magnet. The two-dimensional a
nd three-dimensional spatial resolutions achievable were as follows: 0
.12 x 0.23 mm (two-dimensional) and 0.35 x 0.35 x 0.35 mm (three-dimen
sional) for the intact joint, and 0.08 x 0.08 mm (two-dimensional) and
0.14 x 0.14 x 0.27 mm (three-dimensional) for the disarticulated join
t. These results demonstrate that magnetic resonance imaging; together
with edge detection and volume rendering, can be used to visualize fo
cal cartilage lesions.