FOOD-RELATED, EXERCISE-INDUCED ANAPHYLAXIS

Four children under 12 years of age with food dependent, exercise indu ced anaphylaxis (EIAn) were investigated. These children and five cont rols performed exercise challenges when fasting and one hour after a m eal without food suspected to predispose to the reaction. Patients the n performed exercise tests after intake of each suspected food. Three out of 15 food-exercise combination challenges were positive, but no r eactions provoked after exercise without intake of suspected foods. Pa tients underwent skin prick tests to foods and serum total and specifi c IgE antibodies were measured. Skin prick test results were positive and PAST results were positive in two of three instances. In case 3, f ood-exercise combination challenges did not provoke any clinical react ion. The diagnosis of food dependent EIAn should be considered in youn g children with EIAn of unknown origin.