SYNTHESIS OF GLUTATHIONE ANALOGS, PEPTIDE NUCLEIC-ACIDS AND PHOSPHONOOLIGOPEPTIDES FROM HETEROCYCLIC IMINES

Synthesis of the title compounds 4, 6 and 8 are described. The glutath ione analogues 4 and peptide nucleic acids 6 were prepared from 3-thia zolines according to the Ugi 4CC-reaction. The phosphonooligopeptides 8 were prepared from N,S- and N,O-heterocyclic imines according to the Arbusov reaction.