Rc. Bernotas et al., THERMAL CLEAVAGE OF OXAZOLIDINE-4,5-DIONES TO IMINES - A SHORT SYNTHESIS OF 3,3-DIMETHYL-7-TRIFLUOROMETHYLISOQUINOLINE-2-OXIDE, Synthetic communications, 26(18), 1996, pp. 3471-3477
A series of oxazolidine-4,5-diones 2 was thermally cleaved to cyclic i
mines 3 in excellent yield. This reaction was utilized in an efficient
synthesis of a 3,4-dihydroisoquinoline-based nitrone 1b.