RADICAL HYSTERECTOMY FOR STAGE IB1 VS IB2 CARCINOMA OF THE CERVIX - DOES THE NEW STAGING SYSTEM PREDICT MORBIDITY AND SURVIVAL

Two hundred twenty-nine patients with Stage IB cervical cancer treated with radical hysterectomy were assigned to the new FIGO substages IB1 (n = 181) and IB2 (n = 48) based on clinical tumor diameter, Our purp ose was to determine the impact of the new staging system for IB1 and IB2 cervical cancer on nodal status and survival, Additionally, we ana lyzed the morbidity of radical hysterectomy in light of the new stagin g system, The complications were similar between the two groups. Para- aortic lymphadenectomy was the only independent predictor of complicat ions (P = 0.00026). Stage IB2 patients did have a significantly worse 5-year survival (72.8%) when compared with IB1 (90.0%) (P = 0.0265). M ultivariate stepwise logistical regression analysis indicated that the new staging system did not have an independent impact on survival, St age acts through nodal status in its impact on survival, Positive lymp h nodes, tumor diameter, and Ponderal Index are all independent predic tors of survival (P = 0.0001), Patients with Stage IB2 carcinoma of th e cervix undergoing radical hysterectomy showed no significant increas e in morbidity when compared with patients with Stage IB1 disease trea ted with the same procedure. (C) 1996 Academic Press, Inc.