M. Colafranceschi et al., MISSED HYSTEROSCOPIC DETECTION OF UTERINE CARCINOMA BEFORE ENDOMETRIAL RESECTION - REPORT OF 3 CASES, Gynecologic oncology, 62(2), 1996, pp. 298-300
Endometrial ablation or resection using hysteroscopy appears to be an
effective treatment for menorrhagia resistant to medical therapy. Thre
e patients with endometrial adenocarcinoma missed in the preoperative
hysteroscopic and histological assessment and subjected to endometrial
resection were collected in a multicenter study, One case was an earl
y adenocarcinoma in the background of late proliferative endometrium i
n a 39-year-old woman. In the other two patients, ages 51 and 68, the
adenocarcinoma developed in a polyp in a background of simple hyperpla
sia. Since hysteroscopy with endometrial biopsy might not be able to e
xclude the presence of an early intrauterine cancer, appropriate selec
tion and accurate evaluation of patients are imperative before ablativ
e surgery. Endometrial resection is preferred over endometrial laser a
blation since it provides additional tissue for histologic examination
. (C) 1996 Academic Press, Inc.