ENDOMETRIOSIS WITH MYXOID CHANGE SIMULATING MUCINOUS ADENOCARCINOMA AND PSEUDOMYXOMA PERITONEI

A case of endometriosis with myxoid change is presented here which rai sed concern for metastatic adenocarcinoma and pseudomyxoma peritonei. This is the second case similar to the one described previously in the literature, A 51-year-old woman underwent repair for an umbilical her nia. The tissue sections of the hernia specimen contained isolated poo ls of mucin surrounded focally by cuboidal-type epithelium. Subsequent CT scan of the abdomen and pelvis revealed a large right adenexal mas s, These clinicopathologic findings raised strong suspicion for adenoc arcinoma and pseudomyxoma peritonei. Intraoperative frozen section of the right ovary showed an endometriotic cyst. She underwent hysterecto my, bilateral salpingoophrectomy, partial omentectomy, and lysis of ad hesions, Permanent sections revealed foci of endometriosis in both ova ries and cervix, Pools of acellular mucin were present in the omentum and bladder peritoneum. There was no evidence of malignancy in any of the specimen. The case illustrates that endometriosis with myxoid chan ge can simulate with mucinous adenocarcinoma and pseudomyxoma peritone i. (C) 1996 Academic Press, Inc.