Objective: To evaluate the potential utility of endometrial stripe thi
ckness in predicting pregnancy outcome in women with an hCG less than
a discriminatory zone. Design: Retrospective case review. Setting: Uni
versity emergency department. Patients: Women who presented with sympt
omatic early pregnancies after a spontaneous conception with an hCG le
vel less than a discriminatory zone evaluated to rule out an ectopic p
regnancy (EP). Interventions: Measure endometrial stripe thickness by
transvaginal ultrasound. Main Outcome Measures: Initial endometrial st
ripe thickness was correlated to eventual pregnancy outcomes. Results:
The mean initial endometrial stripe thickness of patients eventually
diagnosed with an intrauterine pregnancy (13.42 +/- 0.68 mm), spontane
ous abortion (9.28 +/- 0.88 mm), and an EP (5.95 +/- 0.35 mm) were all
statistically different from each other. Ninety-seven percent of preg
nancies found to have an endometrial stripe thickness less than or equ
al to 8 mm were abnormal (EP or spontaneous abortion). Conclusions: Th
is study suggest a role of the evaluation of the endometrial stripe th
ickness in the detection of abnormal pregnancies in patients presentin
g for evaluation of a symptomatic early pregnancy with an hCG below a
discriminatory zone. Initial endometrial stripe thickness measured in
patients with an EP is significantly thinner than in those with an int
rauterine pregnancy.