APPLICATION OF CARBOXYMETHYLCELLULOSE IN CONTROLLED DRUG-RELEASE

Authors
SUNGUR S EMREGUL E
Citation
S. Sungur et E. Emregul, APPLICATION OF CARBOXYMETHYLCELLULOSE IN CONTROLLED DRUG-RELEASE, Journal of macromolecular science. Pure and applied chemistry, A33, 1996, pp. 319-325
Citations number
9
Categorie Soggetti
Polymer Sciences
Journal title
Journal of macromolecular science. Pure and applied chemistry → ACNP
ISSN journal
10601325
Volume
A33
Year of publication
1996
Supplement
5-6
Pages
319 - 325
Database
ISI
SICI code
1060-1325(1996)A33:<319:AOCICD>2.0.ZU;2-O
Abstract
Controlled drug release was investigated by using Carboxymethylcellulo se as carrier and erythromycin as model drug. Carboxymethylcellulose w as chosen because of its biologically inert characteristics. It was cr osslinked by ferric salts to obtain biodegradable beads. Controlled re lease was improved by coating with gelatin/caboxymethylcellulose and b y crosslinking with ferric salts/chromium sulfate.