Z. Harel et al., ADOLESCENTS REASONS FOR AND EXPERIENCE AFTER DISCONTINUATION OF THE LONG-ACTING CONTRACEPTIVES DEPO-PROVERA AND NORPLANT, Journal of adolescent health, 19(2), 1996, pp. 118-123
Purpose: The objectives of this study were to examine the reasons for
discontinuation of the long-acting contraceptives Depo-Provera and Nor
plant in adolescents, and to assess the adolescents' experience after
discontinuation of the methods. Methods: A total of 35 adolescents [gy
necologic age 4.7 +/- 0.3 years, and body mass index (BMI) 24.2 +/- 0.
6] who discontinued Depo-Provera, and 31 adolescents (gynecologic age
3.4 +/- 0.3 years, BMI 24.1 +/- 0.9) who discontinued Norplant(R) were
periodically assessed during use of the methods and up to 12 months a
fter discontinuation. Results: The most common reasons for discontinua
tion of both Norplant (after 21.8 +/- 1.6 months of use) and Depo-Prov
era (9.2 +/- 0.9 months of use) were irregular menstrual bleeding (64%
), weight gain (41%), and increased headaches (30%). Resumption of men
strual regularity and dysmenorrhea was noted sooner after discontinuat
ion of Norplant, compared with Depo-Provera. The increase in BMI noted
at discontinuation of Depo-Provera (1.1, P = .0005) and Norplant (1.3
, P = .03) persisted up to 6 months after discontinuation of either me
thod (0.6, P = .01 post-Depo-Provera discontinuation; and 0.9, P = 0.0
2 post-Norplant discontinuation). Only 62% of the adolescents reported
no break in contraceptive practice. The condom was the most popular m
ethod (37%) after discontinuation of Depo-Provera, and oral contracept
ive (39%) after discontinuation of Norplant. The cumulative conception
proportion reached 0.93 at 12 months after discontinuation of Norplan
t, and was significantly higher (P = .01) compared with the cumulative
proportion of conception after discontinuation of Depo-Provera (P = .
50). Conclusions: Health care providers should aggressively manage phy
sical problems associated with Depo-Provera and Norplant use, and expe
dite the transition to a new contraceptive method to minimize the high
pregnancy rate observed after discontinuation of these methods in ado
lescents.