Ga. Kaplan et al., PERCEIVED HEALTH-STATUS AND MORBIDITY AND MORTALITY - EVIDENCE FROM THE KUOPIO ISCHEMIC-HEART-DISEASE RISK FACTOR STUDY, International journal of epidemiology, 25(2), 1996, pp. 259-265
Background. Previous studies have reported an increased risk of death
in those who report their health is poor, however the role of underlyi
ng and subclinical disease in this association has not been carefully
studied. Methods. The associations between perceived health status and
mortality from all causes and cardiovascular disease, incidence of my
ocardial infarction, carotid atherosclerosis, forced expiratory volume
, and maximal exercise capacity were studied in the Kuopio Ischaemic H
eart Disease Risk Factor Study, a population-based study of 2682 men,
aged 42-60, in eastern Finland. Results. There were strong, statistica
lly significant, age-adjusted associations between level of perceived
health and mortality from all causes (RH(bad versus good) = 3.67), car
diovascular causes (RH(bad versus good) = 6.64), and incidence of myoc
ardial infarction (RH(bad versus good) = 3.87). Perceived health level
s were strongly associated with risk factors and disease indicators. T
he associations with mortality and myocardial infarction outcomes were
considerably weakened with progressive adjustment for eight risk fact
ors and prevalent disease. Higher levels of perceived health ware asso
ciated with less carotid atherosclerosis, and greater forced expirator
y volume and maximal exercise capacity. Associations between level of
perceived health and these indicators were considerably stronger in th
ose with prevalent diseases than in those who were healthy. Conclusion
s. The overall pattern of results suggests that perceived health level
s mainly reflect underlying disease burden.