SYNTHESIS OF FUNCTIONALIZED CYCLIC IMINES BY ADDITION OF GRIGNARD-REAGENTS TO OMEGA-BROMONITRILES AND GAMMA,DELTA-UNSATURATED NITRILES

Authors
FRY DF BROWN M MCDONALD JC DIETER RK
Citation
Df. Fry et al., SYNTHESIS OF FUNCTIONALIZED CYCLIC IMINES BY ADDITION OF GRIGNARD-REAGENTS TO OMEGA-BROMONITRILES AND GAMMA,DELTA-UNSATURATED NITRILES, Tetrahedron letters, 37(35), 1996, pp. 6227-6230
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
35
Year of publication
1996
Pages
6227 - 6230
Database
ISI
SICI code
0040-4039(1996)37:35<6227:SOFCIB>2.0.ZU;2-1
Abstract
Trimethylsilyloxy omega-bromonitriles and trimethylsilyloxy-gamma,delt a-unsaturated nitriles give clean 1,2-addition products with Grignard reagents that can be induced to undergo subsequent cyclization either directly or by addition of N-bromosuccinimide, respectively. Copyright (C) 1996 Elsevier Science Ltd