MULTIPLY BRIDGED ACETYLENIC THIACYCLOPHANES

Authors
ENSLEY HE MAHADEVAN S MAGUE J
Citation
He. Ensley et al., MULTIPLY BRIDGED ACETYLENIC THIACYCLOPHANES, Tetrahedron letters, 37(35), 1996, pp. 6255-6258
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
35
Year of publication
1996
Pages
6255 - 6258
Database
ISI
SICI code
0040-4039(1996)37:35<6255:MBAT>2.0.ZU;2-7
Abstract
The 4,17,30-trithia-[7(3)](1,3,5)cyclophane (1) has been prepared by a two-stage, palladium assisted coupling of propargylOTHP with 1,3,5-tr ibromobenzene, followed by sulfide ring closure. The intermediate (8) on deprotection, followed by bromination and reaction with Na2S gives 1 in 58% yield. Copyright (C) 1996 Elsevier Science Ltd