TOTAL SYNTHESIS OF HEMIBREVETOXIN-B

Authors
MORIMOTO M MATSUKURA H NAKATA T
Citation
M. Morimoto et al., TOTAL SYNTHESIS OF HEMIBREVETOXIN-B, Tetrahedron letters, 37(35), 1996, pp. 6365-6368
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
35
Year of publication
1996
Pages
6365 - 6368
Database
ISI
SICI code
0040-4039(1996)37:35<6365:TSOH>2.0.ZU;2-4
Abstract
Total synthesis of hemibrevetoxin B was stereoselectively accomplished based on a novel double rearrangement-ring expansion of a 6,6-membere d ether to a 7,7-membered ether, an exclusive 6-endo-cyclization of hy droxy styrylepoxide, and a direct introduction of a C-4 unit as the si de chain on the A-ring. Copyright (C) 1996 Elsevier Science Ltd