A prospective double-masked placebo controlled trial to assess the pot
ential benefit of topical diclofenac in the treatment of corneal rust
ring of 40 patients attending the eye casualty department was carried
out. Patients allocated to the diclofenac group had significantly redu
ced pain scores at 48 hours after starting treatment compared with pat
ients allocated to the placebo group (p = 0.008 and p = 0.042 for visu
al analogue and Likert pain scales respectively). No difference was no
ted between groups in terms of rate of epithelial healing or degree of
inflammation. Topical diclofenac offers improved analgesia in the tre
atment of corneal rust ring.