SYNTHESIS OF POTENTIAL PEPTIDOMIMETICS BASED ON HIGHLY SUBSTITUTED GLUCOSE AND ALLOSE SCAFFOLDS

Authors
LEDIGUARHER T BOUDON A ELWELL C PATERSON DE BILLINGTON DC
Citation
T. Lediguarher et al., SYNTHESIS OF POTENTIAL PEPTIDOMIMETICS BASED ON HIGHLY SUBSTITUTED GLUCOSE AND ALLOSE SCAFFOLDS, Bioorganic & medicinal chemistry letters, 6(16), 1996, pp. 1983-1988
Citations number
30
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
6
Issue
16
Year of publication
1996
Pages
1983 - 1988
Database
ISI
SICI code
0960-894X(1996)6:16<1983:SOPPBO>2.0.ZU;2-Q
Abstract
A series of eight potential peptidomimetics has been synthesised based on the use of gluco- and allo- carbohydrate derivatives as scaffolds to support appropriate side-chains which mimic the D- and L-aminoacid residues of the cyclic peptide endothelin antagonist BQ123. Copyright (C) 1996 Elsevier Science Ltd.