This study documents the course of submission of a group of biomedical
research papers to peer-reviewed journals and characterizes their qua
lity through citation analysis for published papers and through a typo
logy of originality for those papers that were never accepted. Of fift
y-nine papers, 47 percent (n = 28) were accepted by the first journal
to which they were submitted 25 percent (n = 15) by the second, and 7
percent (n = 6) by the third to sixth journal. For the first five year
s of publication, the average citation rate per year was 1.5, and 43 p
ercent had more than I citation per year Fifteen papers (25 percent) w
ere never accepted. Typologic analysis of five of these papers suggest
s some standards by which it may be possible to characterize scientifi
c originality.