M. Pallavicini et al., A NEW CONVENIENT SYNTHESIS OF 1-(4-NITROPHENYL)-ETHYLAMINE FROM ACETOPHENONE, Journal of chemical research. Synopses, (7), 1996, pp. 330-331
1-(4-Nitrophenyl)ethylamine is prepared directly from acetophenone by
treatment with ammonium formate, nitration of crude 1-phenylethylforma
mide and hydrolysis of the amidic bond; on the basis of the moderate y
ield and the large availability of the starting material, this simple
procedure can be favourably compared with those previously reported.