SELECTION OF A HIGHLY PRODUCTIVE, THERMOACIDOTOLERANT, ETHANOL-ASSIMILATING STRAIN OF CANDIDA-KRUSEI AND INVESTIGATION OF ITS PHYSIOLOGICALFEATURES

The highly productive thermo- and acidotolerant ethanol-assimilating s train VSB-896 of Candida krusei, capable of growth at 40 degrees C and pH 3.5, was obtained as a result of the process of the autoselection of spontaneous and induced mutants on the basis of such parameters as enhanced growth rate and thermo- and acidotolerance. The mutagen N-nit rosomethylurea proved to be efficient in increasing the mutation frequ ency with regard to these characteristics. Optimization of the microel ement composition of the nutrient medium with respect to the contents of Cu2+, Mo6+, B3+, and Co2+ resulted in a decrease in the K-s value.