LEUPROLIDE SUPPRESSION OF ANDROGEN SECRETION BY HILUS CELL HYPERPLASIA WITHIN THE WALL OF AN OVARIAN-CYST

Authors
DESANTIAGO M HERRANZ L ORDAS J ATIENZA M SUAREZMIER M GANCEDO PG
Citation
M. Desantiago et al., LEUPROLIDE SUPPRESSION OF ANDROGEN SECRETION BY HILUS CELL HYPERPLASIA WITHIN THE WALL OF AN OVARIAN-CYST, Clinical endocrinology, 45(2), 1996, pp. 239-242
Citations number
18
Categorie Soggetti
Endocrynology & Metabolism
Journal title
Clinical endocrinology → ACNP
ISSN journal
03000664
Volume
45
Issue
2
Year of publication
1996
Pages
239 - 242
Database
ISI
SICI code
0300-0664(1996)45:2<239:LSOASB>2.0.ZU;2-A
Abstract
Androgenic manifestations coexisting with hilus cell hyperplasia adjac ent to a tumour or an ovarian cyst are extremely rare. We report the c ase of a post-menopausal woman with hirsutism associated with hilus ce ll hyperplasia within the wall of an ovarian cyst. The pattern of ster oid secretion revealed increased testosterone release. Suppression of testosterone to 'normal range' was seen in response to leuprolide admi nistration. This new approach demonstrates gonadotrophin dependence of hilus cell hyperplasia within an ovarian cyst.