S. Watano et al., CONTROL OF GRANULE GROWTH IN FLUIDIZED-BED GRANULATION BY AN IMAGE-PROCESSING SYSTEM, Chemical and Pharmaceutical Bulletin, 44(8), 1996, pp. 1556-1560
In this paper, the control of granule growth in fluidized bed granulat
ion was carried out using a newly developed image processing system, G
ranule images measured by a particle image probe? were digitized by an
image processing system during granulation to continuously calculate
granule size distribution. To avoid excessive granule growth, fuzzy lo
gic using a linguistic algorithm employing if-then rules with a proces
s lag element taken into consideration was adopted for the control alg
orithm, This newly de, eloped system was applied to actual fluidized b
ed granulation under various powder samples and operating conditions,
and the validity of the system was investigated. It was found that the
system could control granule growth with high accuracy, regardless of
changes in powder samples and operating conditions.