CONTROL OF GRANULE GROWTH IN FLUIDIZED-BED GRANULATION BY AN IMAGE-PROCESSING SYSTEM

Citation
S. Watano et al., CONTROL OF GRANULE GROWTH IN FLUIDIZED-BED GRANULATION BY AN IMAGE-PROCESSING SYSTEM, Chemical and Pharmaceutical Bulletin, 44(8), 1996, pp. 1556-1560
Citations number
15
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
ISSN journal
00092363
Volume
44
Issue
8
Year of publication
1996
Pages
1556 - 1560
Database
ISI
SICI code
0009-2363(1996)44:8<1556:COGGIF>2.0.ZU;2-#
Abstract
In this paper, the control of granule growth in fluidized bed granulat ion was carried out using a newly developed image processing system, G ranule images measured by a particle image probe? were digitized by an image processing system during granulation to continuously calculate granule size distribution. To avoid excessive granule growth, fuzzy lo gic using a linguistic algorithm employing if-then rules with a proces s lag element taken into consideration was adopted for the control alg orithm, This newly de, eloped system was applied to actual fluidized b ed granulation under various powder samples and operating conditions, and the validity of the system was investigated. It was found that the system could control granule growth with high accuracy, regardless of changes in powder samples and operating conditions.