Bone mass measurements were performed in a group of 100 healthy women
(ages 22-74 years) with both a densitometric technique measuring ultra
sound bone velocity (UBV) at the distal metaphyses of the first phalan
ges of the hand and single-photon absorptiometry (SPA) applied at the
distal forearm and ultradistal radius, A significant (p < 0.00001) dif
ference was found in both UBV and bone mineral density (BMD) values be
tween premenopausal and postmenopausal women. Simple regression analys
is showed a highly significant relationship (p < 0.0001) between UBV m
easured at proximal phalanges and BMD measured at the distal forearm (
r = 0.693) and ultradistal radius (r = 0.643), There was no correlatio
n between age and both UBV and BMD in premenopausal women. By contrast
, a significant correlation was found between UBV and age in postmenop
ausal women (p < 0.0001; r = 0.510). A similar correlation with age wa
s found for BMD measured at the distal forearm (p < 0.0001; r = 0.458)
and ultradistal radius (p ( 0.0002; r = 0.435). Changes of UBV were a
lso significantly related to years since menopause (p < 0.0001; r = 0.
526), as were BMD variations at the distal forearm (p < 0.0001; r = 0.
451) and ultradistal radius (p < 0.008; r = 0.402). The reproducibilit
y of the methods (coefficient of variation) was 0.46% for UBV and 0.92
% for SPA. Our findings seem to indicate that UBV measured at the phal
anges may have the same clinical applications as BMD measured at the d
istal forearm and ultradistal radius.