Gr. Oetzel, EFFECT OF CALCIUM-CHLORIDE GEL TREATMENT IN DAIRY-COWS ON INCIDENCE OF PERIPARTURIENT DISEASES, Journal of the American Veterinary Medical Association, 209(5), 1996, pp. 958
Objective-To determine effect of prophylactic treatment of dairy cattl
e with a calcium chloride gel on serum calcium concentration in the im
mediate postpartum period and incidence of parturient paresis, retaine
d fetal membranes, and displacement of the abomasum. Design-Randomized
controlled trial. Animals-204 Holstein cows. Procedure-Cows were pair
ed according to parity, whether they had previously had parturient par
esis, and expected calving date. Cows in the treatment group received
doses of calcium chloride gel 12 hours before expected carving, at cal
ving, and 12 and 24 hours after calving. Cows in the control group did
not receive calcium chloride gel. Results-Compared with concentration
in the control COWS, mean serum calcium concentration in cows treated
with calcium chloride gel was significantly increased on postcalving
days 1 and 2. The increase was significant only in cows that were thir
d parity or greater. Calcium chloride gel treatment also resulted in s
ignificantly reduced incidence of parturient paresis, parturient hypoc
alcemia, and displaced abomasum. The incidence of parturient paresis w
as lower in cows that received the precalving dose of calcium chloride
gel (0/39) than in cows that did not receive the precalving dose (5/6
3). Clinical implications-Results suggest that periparturient prophyla
ctic treatment of dairy cattle with an oral calcium chloride gel may b
e beneficial and that treatment would be most effective for cows of th
ird parity or greater. Administration of a precalving dose of calcium
chloride gel is necessary to reduce the incidence of parturient paresi
s, but postcalving treatment alone has other beneficial effects.