ASYMMETRIC ALLYLATION OF AROMATIC-ALDEHYDES USING CHIRAL ALLYLIC TIN REAGENTS

Authors
NISHIDA M TOZAWA T YAMADA K MUKAIYAMA T
Citation
M. Nishida et al., ASYMMETRIC ALLYLATION OF AROMATIC-ALDEHYDES USING CHIRAL ALLYLIC TIN REAGENTS, Chemistry Letters, (12), 1996, pp. 1125-1126
Citations number
18
Categorie Soggetti
Chemistry
Journal title
Chemistry Letters → ACNP
ISSN journal
03667022
Issue
12
Year of publication
1996
Pages
1125 - 1126
Database
ISI
SICI code
0366-7022(1996):12<1125:AAOAUC>2.0.ZU;2-N
Abstract
Chiral allylating reagents, readily generated in situ from 2 lambda(2) -1,3,2-benzodioxastannole [Sn-II(O2C6H4)], allyl halides, chiral dialk yl tartrates and 1,8-diazabicyclo[5.4.0]-7-undecene (DBU) smoothly rea ct with aromatic aldehydes at -78 degrees C in the presence of a catal ytic amount of copper salts to afford the corresponding homoallylic al cohols in high yields with high enantioselectivities.