SYNTHESIS OF 1-ARYLAMINOCARBONYL-3-BENZYL THIO-4-CARBETHOXY (OR CYANO)-5-AMINOPYRAZOLE

1-Arylaminocarbonyl-3-benzylthio-4-carbethoxy (or cyano)-5-aminopyrazo les (3) were synthesized by the reaction of the 5-amino-3-benzylthio-4 -carbethoxy (or cyano) pyrazole with the aryl isocyanate, It was found that there were great influence of the property and position of subst ituents X, Yon the chemical shift of H-(N2) in H-1 NMR spectra, By mea ns of molecular mechanics calculations, the substituent effect on the chemical shift of H -(N2) was rationalized, The preliminary bioassay s hows that some compounds have herbicidal activities.