AN EVALUATION OF THE EFFECTS OF SUSCEPTIBILITY CHANGES ON THE WATER CHEMICAL-SHIFT METHOD OF TEMPERATURE-MEASUREMENT IN HUMAN PERIPHERAL MUSCLE

Divergencies between chemical shift measurements of temperature and di rectly measured values using optical sensors have been studied in vivo in human peripheral muscle with the assistance of a variety of experi mental and theoretical techniques, These include the modeling of both thermal and susceptibility changes using two- and three-dimensional fi nite element methods, as well as the use of multi-wavelength near infr ared observations, The conclusion of these studies is that a simple te mperature calibration is not accessible, with results affected by the complex response of the tissue itself.