SESQUITERPENE PEROXIDES FROM SENECIO-SELLOI AND EUPATORIUM-RUFESCENS

Authors
RUCKER G SCHENKEL EP MANNS D MAYER R HEIDEN K HEINZMANN BM
Citation
G. Rucker et al., SESQUITERPENE PEROXIDES FROM SENECIO-SELLOI AND EUPATORIUM-RUFESCENS, Planta medica, 62(6), 1996, pp. 565-566
Citations number
9
Categorie Soggetti
Pharmacology & Pharmacy","Plant Sciences","Chemistry Medicinal
Journal title
Planta medica → ACNP
ISSN journal
00320943
Volume
62
Issue
6
Year of publication
1996
Pages
565 - 566
Database
ISI
SICI code
0032-0943(1996)62:6<565:SPFSAE>2.0.ZU;2-2
Abstract
Two bisabolane-type sesquiterpenes, zingiberene-3,6-beta-endoperoxide (1) and zingiberene-3,6-alpha-endoperoxide (2) have been isolated from the aerial parts of Senecio selloi and Eupatorium rufescens. Their st ructures were determined by spectroscopic methods. Both compounds show schizonticidal activity against Plasmodium falciparum (EC(50) = 10 mu g/ml).