NEUROPSYCHOLOGICAL CORRELATES OF URINE TOXICOLOGY RESULTS

1. The present study evaluated neuropsychological differences among 4 groups of men and women, aged 15 to 61 years. The groups were defined on the basis of urine toxicology screens indicating recent cocaine (n= 12), cannabis (n=14), or multiple drug (n=7) use, or no such use (n=21 ). 2. The Wechsler Adult Intelligence Scale-Revised (WAIS-R), the Trai l Making Tests, and the Porteus Maze Test were administered to all sub jects. 3. Analyses revealed no significant differences between the gro ups in age, gender composition, or in the proportion of group members with personal histories of alcohol/drug abuse or dependence, or Anti-S ocial Personality Disorder. 4. The cocaine positive group exhibited st atistically significant impairments in Verbal IQ, as well as on Inform ation, Vocabulary, Comprehension, Picture Completion, and Trails B sub tests. The other experimental groups did not differ from the urine neg ative group.