3-DIMENSIONAL CYCLODEXTRIN - A NEW CLASS OF HOSTS BY TREHALOSE CAPPING OF BETA-CYCLODEXTRIN

Authors
CUCINOTTA V GRASSO G PEDOTTI S RIZZARELLI E VECCHIO G
Citation
V. Cucinotta et al., 3-DIMENSIONAL CYCLODEXTRIN - A NEW CLASS OF HOSTS BY TREHALOSE CAPPING OF BETA-CYCLODEXTRIN, Journal of inclusion phenomena and molecular recognition in chemistry, 25(1-3), 1996, pp. 39-42
Citations number
10
Categorie Soggetti
Chemistry,Crystallography
Journal title
Journal of inclusion phenomena and molecular recognition in chemistry → ACNP
ISSN journal
09230750
Volume
25
Issue
1-3
Year of publication
1996
Pages
39 - 42
Database
ISI
SICI code
0923-0750(1996)25:1-3<39:3C-ANC>2.0.ZU;2-N
Abstract
In order to obtain better abiotic receptors for analytical and kinetic applications, the new capped derivative of cyclomaltoheptaose (CDTH) was synthesized by reaction of deoxy-6,6'-di(S-cysteamine)-alpha,alpha '-trehalose with 6A,6D-dideoxy-6A,6D-diiodo-cyclo-maltoheptaose. The C DTH-ACS (anthraquinone-2-sulfonic acid sodium salt) system was investi gated. by H-1 NMR spectroscopy and by i.c.d. (induced circular dicrois m), and a deep inclusion of ACS inside the CDTH cavity, with an associ ation constant about six times larger with respect to ACS - beta-CD sy stem was found.